Response to Heard et al

Response to Heard et al.

H eard et al (2015) generated cIap1 / Xiap / mice and were surprised to find them to be viable and fertile, because we had reported (Moulin et al, 2012) that cIap1 / Xiap / mice died by day E12.5 of embryogenesis (Moulin et al, 2012 Figs 1B and 2B and Supplementary Fig S1A). We are working with Heard et al (2015) in an attempt to determine why. It is, however, clear that failure of our cIap2cIa...

Public Participation: Methods Matter; A Response to Boaz et al.

Response to Sadek et al. and Kotlikoff et al.

Ditte Caroline Andersen,1,2,* Charlotte Harken Jensen,1 and Søren Paludan Sheikh1,3 1Laboratory of Molecular and Cellular Cardiology, Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, 5000 Odense C, Denmark 2Clinical Institute/University of Southern Denmark, 5000 Odense C, Denmark 3Institute of Molecular Medicine/University of Southern Denmark, 5000 Odense C, Den...

In Response to Fakruddin et al. and Apostolou et al

In Response to Fakruddin et al. dicted to result in substitutions of amino acids at the and Apostolou et al. corresponding positions in the protein sequence. In each of these cases, individual tumor DNA samples possessed the same sequence as that of the corresponding cell line. We agree with many of the above findings, including To determine if the divergent sequences represented the frequency ...

Response to Hofmann et al

same RHAMM1v4 isoform expressed in the same cells RHAMM belongs to a group of hyaladherins that reguwas later reported to be located exclusively in the cytolate cell motility and cell cycle and that are expressed plasm (Zhang et al., 1998). in the cytoplasm, nucleus, and cell surface, in spite of Questions about the physiological significance of the a lack of signal peptide or transmembrane dom...